Fixseq – Universal count correction for high-throughput sequencing

March 11, 2014 Leave a comment 10,640 Views

Researchers at MIT show that existing RNA-seq, DNase-seq, and ChIP-seq data exhibit overdispersed per-base read count distributions that are not matched to existing computational method assumptions. To compensate for this overdispersion we introduce a nonparametric and universal method for processing ...

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Fixseq – Universal count correction for high-throughput sequencing

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