Intratumoral heterogeneity of cancer cells and tumor-infiltrating immune cells is increasingly being viewed as a key factor driving tumor progression and response to therapy. Over the past several years, technological advances have created powerful...
Read More »Webinar Recording Available – Combining scRNA-Seq and Flow Cytometry
Learn how to use Dimensionality Reduction, Clustering and Hierarchial Gating, and Geneset Enrichment Analysis! Systems biology is poised to revolutionize our understanding of disease models and multi-omics studies as exemplified here are a key step along that exciting journey of ...
Read More »Quartz-Seq2 – a high-throughput single-cell RNA-sequencing method that effectively uses limited sequence reads
High-throughput single-cell RNA-seq methods assign limited unique molecular identifier (UMI) counts as gene expression values to single cells from shallow sequence reads and detect limited gene counts. RIKEN institute researchers have developed a high-throughput single-cell RNA-seq method, Quartz-Seq2, to overcome ...
Read More »Tumor Heterogeneity, Single-Cell Sequencing, and Drug Resistance
Tumor heterogeneity has been compared with Darwinian evolution and survival of the fittest. The evolutionary ecosystem of tumors consisting of heterogeneous tumor cell populations represents a considerable challenge to tumor therapy, since all genetically and phenotypically different subpopulations have to ...
Read More »Postdoc Position Available – Singapore Immunology Network
from naturejobs.com A Postdoctoral Research Fellow position is available in the new team within the Bioinformatics group in Singapore Immunology Network (SIgN) targeting at single-cell data analysis and integration. Single-cell technologies such as mass cytometry and single-cell RNA-seq/DNA-seq allow for ...
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