Tag Archives: fluorescent in situ RNA sequencing

An important step toward understanding gene regulation is the elucidation of the time necessary for the completion of individual steps. Measurement of reaction rates can reveal potential nodes for regulation. For example, measurements of in vivo transcription elongation rates reveal ...

RNA-sequencing (RNA-seq) measures the quantitative change in gene expression over the whole transcriptome, but it lacks spatial context. In contrast, in situ hybridization provides the location of gene expression, but only for a small number of genes. Here researchers from ...

from Genetic Engineering News by Anton Simeonov, Ph.D. This literature review highlights a study led by George Church describing FISSEQ, or fluorescent in situ RNA sequencing. Methods such as fluorescence in situ hybridization (FISH) allow gene expression to be observed ...