Tag Archives: Functional enrichment

With new technological developments, the number of sequencing applications is continuously expanding, while at the same time sequencing prices are falling. This is resulting in an exponential increase in sequencing data. However, while ‘big data’ brings more...

Over-representation analysis (ORA) detects enrichment of genes within biological categories. Gene Ontology (GO) domains are commonly used for gene/gene-product annotation. When ORA is employed, often times there are hundreds of statistically significant GO terms per gene set. Comparing enriched categories ...