Combining RNA-Seq Proteogenomics and Global Post-Translational Modification (G-PTM) Search Strategy Reveals Human Proteomic Variation

December 30, 2015 Leave a comment 4,185 Views

Mass spectrometry-based proteomic analysis underestimates proteomic variation due to the absence of variant peptides and posttranslational modifications (PTMs) from standard protein databases. Each individual carries thousands of missense mutations that lead to single amino acid variants, but these are missed ...

RNA-Seq Blog Transcriptome Research & Industry News

Tag Archives: G-PTM

Combining RNA-Seq Proteogenomics and Global Post-Translational Modification (G-PTM) Search Strategy Reveals Human Proteomic Variation

Performance assessment of sample-specific network control methods for bulk and single-cell biological data analysis

Single-nucleus RNA sequencing explains why some neurons are more susceptible than others in Alzheimer’s disease

RNA-Seq data suggests that exitron splicing represents an additional cancer-driving mechanism beyond genetic alterations

SPEAQeasy – a scalable pipeline for expression analysis and quantification for R/bioconductor-powered RNA-seq analyses

ac4C-seq – quantitative nucleotide resolution profiling of RNA cytidine acetylation

Trips-Viz: an environment for the analysis of public and user-generated ribosome profiling data

IsoSeek – unbiased and UMI-informed sequencing of cell-free miRNAs at single-nucleotide resolution