RNA-Seq has supplanted microarrays as the preferred method of transcriptome-wide identification of differentially expressed genes. However, RNA-Seq analysis is still rapidly evolving, with a large number of tools available for each of the three major processing steps: read alignment, expression ...
Read More »Pathway Analysis and Omics Data Visualization Using Pathway Genome Databases
The species-specific plant Pathway Genome Databases (PGDBs) based on the BioCyc platform provide a conceptual model of the cellular metabolic network of an organism. Such frameworks allow analysis of the genome-scale expression data to understand changes in the overall metabolisms ...
Read More »Lexogen and Bluebee collaborate to simplify gene expression analysis of RNA-Seq data
VIENNA, Austria and RIJSWIJK, The Netherlands, Oct. 19, 2016 /PRNewswire/ — Today Lexogen, a transcriptomics and next generation sequencing company, announces collaboration with Bluebee, a leading provider of high-performance genomics solutions, for implementation of QuantSeq data analysis pipeline on the Bluebee ...
Read More »A High Resolution Map of the Arabidopsis thaliana Developmental Transcriptome Based on RNA-seq Profiling
Arabidopsis thaliana is a long established model species for plant molecular biology, genetics and genomics, and studies of A.thaliana gene function provide the basis for formulating hypotheses and designing experiments involving other plants, including economically important species. A comprehensive understanding ...
Read More »CAMUR – Knowledge extraction from RNA-Seq cancer data through equivalent classification rules
Nowadays, knowledge extraction methods from Next Generation Sequencing data are highly requested. In this work, researchers at the National Research Council, Italy focus on RNA-seq gene expression analysis and specifically on case-control studies with rule-based supervised classification algorithms that build ...
Read More »A comparison of commercially-available total RNA extraction kits
This study compared the performance of five commercially available kits in extracting total RNA from small eukaryotic tissue samples (<15 mg). Total RNA was isolated from fathead minnow (Pimephales promelas) tissues (spleen, blood, kidney, embryo, and larvae) using the Qiagen RNeasy® ...
Read More »Computational Method Dramatically Speeds Up Estimates of Gene Expression, CMU, UMD Researchers Report
“Sailfish” Method Could Pay Dividends as Genomic Medicine Expands Contact: Byron Spice / 412-268-9068 / bspice@cs.cmu.edu PITTSBURGH—With gene expression analysis growing in importance for both basic researchers and medical practitioners, researchers at Carnegie Mellon University and the University of Maryland ...
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