Mammalian genomes encode for thousands of microRNAs, which can potentially regulate the majority of protein-coding genes. They have been implicated in development and disease, leading to great interest in understanding their function, with computational methods being widely used to predict ...
Read More »Gene expression read results are influenced by RNA quality
Researchers at the University of Southern California examined the performance of three RNA-Sequencing library preparation protocols as a function of RNA integrity, comparing gene expressions between heat-degraded samples to their high-quality counterparts. This work is invaluable given the difficulty of ...
Read More »Comparison of RNA-Seq and Microarray in Transcriptome Profiling
To demonstrate the benefits of RNA-Seq over microarray in transcriptome profiling, researchers at Janssen Research & Development performed both RNA-Seq and microarray analyses on RNA samples from a human T cell activation experiment. In contrast to other reports, their analyses ...
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