mRIN – direct assessment of genome-wide and gene-specific mRNA integrity from large-scale RNA-sequencing data

August 6, 2015 Leave a comment 2,812 Views

The volume of RNA-Seq data sets in public repositories has been expanding exponentially, providing unprecedented opportunities to study gene expression regulation. Because degraded RNA samples, such as those collected from post-mortem tissues, can result in distinct expression profiles with potential ...

RNA-Seq provides first global analysis of regulated splicing alterations in cancer

April 28, 2015 Leave a comment 4,045 Views

Cancer is a complex disease that involves aberrant gene expression regulation. Discriminating the modified expression patterns driving tumor biology from the many that have no or little contribution is important for understanding cancer molecular basis. Recurrent deregulation patterns observed in ...

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Tag Archives: gene expression regulation

mRIN – direct assessment of genome-wide and gene-specific mRNA integrity from large-scale RNA-sequencing data

RNA-Seq provides first global analysis of regulated splicing alterations in cancer

RNA sequencing brings hope for endangered wild cats

Mim-tRNAseq – A method that accurately measures the abundance and modification status of different tRNAs

Uncovering the Anti-Myeloma Resistance Files

Long term and short-term effects of RNA fixation on Single Cell RNA Sequencing

Single cell RNA sequencing opens new avenues for eradicating leukaemia at its source

2passtools: two-pass alignment using machine-learning-filtered splice junctions increases the accuracy of intron detection in long-read RNA sequencing

scRNA-Seq reveals a new type of bone cell that may uncover therapeutic targets for a range of skeletal diseases