RNA-Seq Blog Transcriptome Research & Industry News
Gene coexpression networks yield critical insights into biological processes, and single-cell RNA sequencing provides an opportunity to target...
Read More »LocCSN – constructing local cell-specific networks from single-cell data
CEMiTool – gene co-expression network analysis
The analysis of modular gene co-expression networks is a well-established method commonly used for discovering the systems-level functionality of genes. In addition, these studies provide a basis for the discovery of clinically relevant molecular pathways underlying different diseases and conditions. ...
Read More »Researchers combine CRISPR gene editing and single cell genomic profiling
A new combined method may finally give scientists a tool fine enough to probe life’s most nuanced processes What combinations of mutations help cancer cells survive? Which cells in the brain are involved in the onset of Alzheimer’s? How do ...
Read More »RNA-Seq reveals how gene network controls flower/fruit production
Cold Spring Harbor, NY — There is staggering diversity in the number of flowers produced by each of the 2,800 or so species of plants in the nightshade family, which includes economically important crops such as tomatoes, peppers, and potatoes. ...
Read More »Identification of novel long non-coding RNAs using RNA-Seq
Functional characterization of long non-coding RNAs (lncRNAs) and their pathological relevance is still a challenging task. Abnormal expression of a few long non-coding RNAs have been found associated with hepatocellular carcinoma, with potential implications to both improve our understanding of ...
Read More »Multiple Postdoctoral Fellowships – Gene Networks in CNS Development and Disorders
Employer – Vollum Institute Website – http://www.lee-labs.com Location – Portland, OR, United States Expires – June 30, 2015 Job type – Postdoctoral Salary – $40,000 – $60,000 Qualifications – Postgraduate – Doctorate/PhD Employment type – Contract Job hours – Full-time ...
Read More »Alternatively spliced microexons are present at abnormal levels in autism brains
from SFARI by Kate Yandell Small pieces of DNA within genes, dubbed ‘microexons,’ are abnormally regulated in people with autism, suggests a study of postmortem brains published 18 December in Cell1. These sequences, some as short as three nucleotides, moderate ...
Read More »Post-doc Postions Available – Texas State University
One or two postdoctoral positions are available immediately in Oncinfo Lab, Department of Computer Science at Texas State University. Position description The successful candidates will contribute to development and application of cutting edge computational methods to analyze RNA-seq and other ...
Read More »SpliceNet: recovering splicing isoform-specific differential gene networks from RNA-Seq data of normal and diseased samples
Conventionally, overall gene expressions from microarrays are used to infer gene networks, but it is challenging to account splicing isoforms. High-throughput RNA Sequencing has made splice variant profiling practical. However, its true merit in quantifying splicing isoforms and isoform-specific exon ...
Read More »cGRNB – combinatorial Gene Regulatory Networks Builder
We are witnessing rapid progress in the development of methodologies for building the combinatorial gene regulatory networks involving both TFs (Transcription Factors) and miRNAs (microRNAs). There are a few tools available to do these jobs but most of them are ...
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