Tag Archives: genetic variants

Bioinformatics methods for various RNA-seq data analyses are in fast evolution with the improvement of sequencing technologies. However, many challenges still exist in how to efficiently process the RNA-seq data to obtain accurate and comprehensive results. Mapping RNA-seq reads to ...

SNiPlay is a web-based tool for detection, management and analysis of genetic variants including both single nucleotide polymorphisms (SNPs) and InDels. Version 3 now extends functionalities in order to easily manage and exploit SNPs derived from next generation sequencing technologies, ...

A practical webinar highlighting genetic data integration approaches featuring Dr. Tuuli Lappalainen. Explore the power of genome and transcriptome data integration, expand your understanding of genetic variants, and map future research applications. In this video you will learn how: Combining ...

10:00 ET New England Biolabs® and Directed Genomics Partner to Develop Novel Target Enrichment Technologies for Next Generation Sequencing  New England Biolabs (NEB®) and Directed Genomics together announce that they have established a partnership to develop a suite of new ...

Massively parallel RNA sequencing (RNA-seq) has yielded a wealth of new insights into transcriptional regulation. A first step in the analysis of RNA-seq data is the alignment of short sequence reads to a common reference genome or transcriptome. Genetic variants ...

Identification of genetic variants affecting splicing in RNA sequencing population studies is still in its infancy. Splicing phenotype is more complex than gene expression and ought to be treated as a multivariate phenotype to be recapitulated completely. Here a team ...

To demonstrate the benefits of RNA-Seq over microarray in transcriptome profiling, researchers at Janssen Research & Development performed both RNA-Seq and microarray analyses on RNA samples from a human T cell activation experiment. In contrast to other reports, their analyses ...