Tag Archives: Genome Institute of Singapore

Projects involve methods development for new transcriptomics technology (single cell RNA-Seq, long read RNA-Seq), statistical modeling of biases in high throughput sequencing data...

Scientists from Agency for Science, Technology and Research’s (A*STAR) Genome Institute of Singapore (GIS), the National Cancer Centre Singapore (NCCS) and Fluidigm Corporation have developed a new technology to simultaneously and systematically...

Current technologies for targeted characterization and manipulation of viral RNA primarily involve amplification or ultracentrifugation with isopycnic gradients of viral particles to decrease host RNA background. The former strategy is non-compatible for characterizing properties innate to RNA strands such as ...

28 Feb 2019 at 11:00 (GMT -06:00) Jonathan Göke – Senior Research Scientist (PI) Genome Institute of Singapore (A*STAR) The ability of RNA-sequencing to generate a high-dimensional, quantitative readout...

Circular RNA (circRNA) is a newly validated class of single-stranded RNA, ubiquitously expressed in mammalian tissues and possessing key functions including acting as microRNA sponges and as transcriptional regulators by binding to RNA-binding proteins. While independent studies confirm the expression ...