With the increasing number of studies focusing on PIWI-interacting RNA (piRNAs), it is now pertinent to develop efficient tools dedicated towards piRNA analysis. Researchers at the National Institute of...
Read More »Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells
Human fetal germ cells (FGCs) are precursors to sperm and eggs and are crucial for maintenance of the species. However, the developmental trajectories and heterogeneity of human FGCs remain largely unknown. Here researchers from the Beijing Advanced Innovation Center for Genomics ...
Read More »Single-cell Transcriptogenomics
Researchers from the Albert Einstein College of Medicine have developed an integrative method, termed Single-Cell Transcriptogenomics (SCTG), in which whole exome sequencing and RNA-seq is performed concurrently on single cells. This methodology enables one to track germline and somatic variants ...
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