Tag Archives: GTEx

Analyzing RNA sequencing data pinpoints ‘somatic clones,’ including some harboring cancer mutations, in many types of normal tissue. Cell division is not perfect. As we get older, mutations often appear in genes in normal cells. Most of these mutated cells ...

Rapidly decreasing cost of next-generation sequencing has led to the recent availability of large-scale RNA-seq data, that empowers the analysis of gene expression variability, in addition to gene expression means. Researchers from the University of Arizona present the MDSeq, based ...

Join us for the fifth and final GTEx Community Scientific meeting. June 28, 2017 in Rockville, MD. The GTEx Community meeting has been an annual event that is open to the scientific community interested in learning more about the project ...

The advent of high-throughput RNA sequencing (RNA-seq) has led to the discovery of unprecedentedly immense transcriptomes encoded by eukaryotic genomes. However, the transcriptome maps are still incomplete partly because they were mostly reconstructed based on RNA-seq reads that lack their ...

The last Neanderthal died 40,000 years ago, but much of their genome lives on, in bits and pieces, through modern humans. The impact of Neanderthals’ genetic contribution has been uncertain: Do these snippets affect our genome’s function, or are they ...

Enhancing the Usage of Human Genomics for the benefit of all April 20-21, 2017 The GTEx Community meeting is held annually and is open to the scientific community who are interested in learning more about the project and data, or ...

Gene expression levels are dynamic molecular phenotypes that respond to biological, environmental, and technical perturbations. Here, University of Washington researchers use a novel replicate classifier approach for discovering transcriptional signatures and apply it to the Genotype-Tissue Expression (GTEx) data set. ...

Barcelona, Spain: Obesity is on the rise throughout the world, and in some developed countries two-third of the adult population is either overweight or obese. This brings with it an increased risk of serious conditions such as heart disease, stroke, ...

Differential expression analysis of RNA sequencing (RNA-seq) data typically relies on reconstructing transcripts or counting reads that overlap known gene structures. Researchers at Johns Hopkins University previously introduced an intermediate statistical approach called differentially expressed region (DER) finder that seeks ...

from Health Canal – Today, the 15th version of the Human Protein Atlas is launched. The new version includes data from different sources, which makes comparisons between tissue profiles on both the RNA and protein level possible. Looking closely at ...