Tag Archives: Harvard Medical School

Coronavirus disease 2019 (COVID-19), the global pandemic caused by SARS-CoV-2, has resulted thus far in greater than 933,000 deaths worldwide; yet...

BostonGene Corporation, a biomedical software company committed to defining optimal precision medicine-based therapies for cancer patients, today announced a scientific collaboration with Brigham and Women’s Hospital, a world-class academic medical center and a major teaching hospital of Harvard Medical School ...

Ribosome profiling (Ribo-seq) is a powerful technology for globally monitoring RNA translation; ranging from codon occupancy profiling, identification of actively translated open reading frames (ORFs), to the quantification of translational efficiency under...

RNA abundance is a powerful indicator of the state of individual cells. Single-cell RNA sequencing can reveal RNA abundance with high quantitative accuracy, sensitivity and throughput1. However, this approach captures only a static snapshot at a point in...

Recent single-cell RNA-seq protocols based on droplet microfluidics use massively multiplexed barcoding to enable simultaneous measurements of transcriptomes for thousands of individual cells. The increasing complexity of such data creates challenges for subsequent computational processing...

Topic:  Single neuron transcriptomic analyses of brain regions regulating hunger, other homeostatic motivational drives, and physiology. Laboratory:   Bradford B. Lowell MD, PhD, Professor of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.   Lab website:  https://www.lowelllab.com Candidates must ...

RNA sequencing (RNA-seq) is a powerful method of transcript analysis that allows for the sequence identification and quantification of cellular transcripts. RNA-seq has many applications including differential gene expression (DE) analysis, gene fusion detection...

A study led by Kevin King, a bioengineer and physician at the University of California San Diego, has found that the immune system plays a surprising role in the aftermath of heart attacks.  The research could lead to new therapeutic ...

Single-cell RNA-seq protocols provide powerful means for examining the gamut of cell types and transcriptional states that comprise complex biological tissues. Recently-developed approaches based on droplet microfluidics, such as inDrop or Drop-seq, use massively multiplexed barcoding to enable simultaneous measurements ...

Similarities and differences among astrocytomas and oligodendrogliomas may suggest new treatment approaches Detailed analysis of two brain tumor subtypes has revealed that they may originate from the same type of neural progenitor cells and be distinguished by gene mutation patterns ...