AuPairWise – a method to estimate RNA-seq replicability through co-expression

March 25, 2016 Leave a comment 2,655 Views

In addition to detecting novel transcripts and higher dynamic range, a principal claim for RNA-sequencing has been greater replicability, typically measured in sample-sample correlations of gene expression levels. Through a re-analysis of ENCODE data, researchers at Cold Spring Harbor Laboratory ...

SPARSE: Quadratic Time Simultaneous Alignment and Folding of RNAs Without Sequence-Based Heuristics

April 8, 2015 Leave a comment 3,093 Views

RNA-Seq experiments have revealed a multitude of novel ncRNAs. The gold standard for their analysis based on simultaneous alignment and folding (Sankoff, 1985) suffers from extreme time complexity of O(n6). Subsequently, numerous faster “Sankoff-style” approaches have been suggested. Commonly, the ...

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Tag Archives: Heuristics

AuPairWise – a method to estimate RNA-seq replicability through co-expression

SPARSE: Quadratic Time Simultaneous Alignment and Folding of RNAs Without Sequence-Based Heuristics

Single-cell RNA and protein expression in relation to cell cycle progression

Evaluating capture sequence performance for single-cell CRISPR activation experiments

Seven Bridges Selected by Pfizer to Support Data Management Solution for Single-Cell RNA Sequencing Data

Single-cell mapper (scMappR) – using scRNA-seq to infer the cell-type specificities of differentially expressed genes

Featured RNA-Seq Job – Staff Bioinformatics Scientist, RNA-Seq

Introduction to NGS – RNA-Seq Data Analysis – DNA Variant Calling

Yale neurologists use RNA sequencing to identify consistent neuroinflammatory response in ICH patients