Tag Archives: hippocampus

Obtaining high quality RNA from complex biological tissues, such as the brain, is needed for establishing high-fidelity cell-type specific transcriptomes. Although combining genetic labeling techniques with laser capture microdissection (LCM) is generally sufficient, concerns over RNA degradation and limited yields ...

Clarifying gene expression in narrowly defined neuronal populations can provide insight into cellular identity, computation, and functionality. Here, researchers at the Howard Hughes Medical Institute used next-generation RNA sequencing (RNA-seq) to produce a quantitative, whole genome characterization of gene expression ...

Researchers at the Howard Hughes Medical Institute’s Janelia Research Campus have uncovered unexpected diversity within a single, canonical cell type of the mammalian brain. Their analysis of cells called CA1 pyramidal neurons shows that for many genes, expression levels vary ...

Scientists have recorded evidence of the brain turning off its memory inhibitor to make new memories In 1953, a man named Henry Molaison underwent a surgery which removed most of his hippocampus in an attempt to cure his epileptic seizures. ...