A Combination of ChIP-seq and RNA-seq reveals H3K4me3 landscape in the human brain

November 19, 2015 Leave a comment 5,899 Views

Regulators of the histone H3-trimethyl lysine-4 (H3K4me3) mark are significantly associated with the genetic risk architecture of common neurodevelopmental disease, including schizophrenia and autism. Typical H3K4me3 is primarily localized in the form of sharp peaks, extending in neuronal chromatin on ...

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