PseudoLasso – correctly align ambiguous reads and accurately estimate the expression level among homologous genes

July 22, 2016 Leave a comment 4,903 Views

RNA-Sequencing has been the leading technology to quantify expression of thousands genes simultaneously. The data analysis of an RNA-Seq experiment starts from aligning short reads to the reference genome/transcriptome or reconstructed transcriptome. However, current aligners lack the sensitivity to distinguish ...

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Tag Archives: homologous genes

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