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  • Learn more about available bioinformatics tools and pipelines to analyze RNA sequencing data
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  • Yale researchers identify tumor reactive immune cells with RNA sequencing to help fight against advanced melanoma
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  • RNA sequencing brings hope for endangered wild cats
  • Mim-tRNAseq – A method that accurately measures the abundance and modification status of different tRNAs
  • Uncovering the Anti-Myeloma Resistance Files
  • Long term and short-term effects of RNA fixation on Single Cell RNA Sequencing
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Tag Archives: HonorHealth

Single-cell RNA sequencing reveals details about individual cells in pancreatic tumors

October 2, 2020 Leave a comment 1,023 Views

rna-seq

TGen and HonorHealth investigators suggest this granular analysis could lead to better treatments for pancreatic cancer patients Led by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and by HonorHealth Research and...

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RNA-SEQ & COVID-19

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Recent RNA-SEQ Pubs

Network pharmacology and RNA-sequencing reveal the molecular mechanism of Xuebijing injection on COVID-19-induced cardiac dysfunction
4 March 2021
Direct Comparative Analyses of 10X Genomics Chromium and Smart-seq2
4 March 2021
Metabolic adjustments during starvation in Daphnia pulex
4 March 2021
SwarnSeq: An improved statistical approach for differential expression analysis of single-cell RNA-seq data
4 March 2021
The overexpression of DNA repair genes in invasive ductal and lobular breast carcinomas: Insights on individual variations and precision medicine
4 March 2021
Detecting cell-type-specific allelic expression imbalance by integrative analysis of bulk and single-cell RNA sequencing data
4 March 2021

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  • pipeComp – a general framework for the evaluation of computational pipelines, reveals performant single cell RNA-seq preprocessing tools
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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)


RNA-Seq

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  • rna-seq

    Learn more about available bioinformatics tools and pipelines to analyze RNA sequencing data

    11 hours ago
  • rna-seq

    New search engine for single cell atlases

    12 hours ago
  • rna-seq

    Yale researchers identify tumor reactive immune cells with RNA sequencing to help fight against advanced melanoma

    13 hours ago
  • rna-seq

    New algorithm identifies ‘escaping’ cells in single-cell CRISPR screens

    1 day ago
  • rna-seq

    RNA sequencing brings hope for endangered wild cats

    1 day ago
  • rna-seq

    Mim-tRNAseq – A method that accurately measures the abundance and modification status of different tRNAs

    2 days ago
  • rna-seq

    Uncovering the Anti-Myeloma Resistance Files

    2 days ago

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