Tag Archives: host

Dengue and Zika viral infections affect millions of people annually and can be complicated by hemorrhage or neurological manifestations, respectively. However, a thorough understanding of the host response to these viruses is lacking...

The ability to simultaneously characterize the bacterial and host expression programs during infection would facilitate a comprehensive understanding of pathogen-host interactions. Although RNA sequencing (RNA-seq) has greatly advanced our ability to study the transcriptomes of prokaryotes and eukaryotes separately, limitations ...

An invasive bacterium must adapt to the environment of the host cell while the host cell reacts to the invader. However, the analysis of transcriptomes to understand changes in host and pathogen gene expression has typically been applied to a ...

Bacteria express many small RNAs for which the regulatory roles in pathogenesis have remained poorly understood due to a paucity of robust phenotypes in standard virulence assays. Here, researchers from the University of Würzburg used a generic ‘dual RNA-seq’ approach ...

Genome-scale analysis of host-pathogen interactions – University of Technology Sydney We are seeking a PhD student to apply leading-edge bioinformatics analysis methods to decipher the interactions of the obligate intracellular human pathogen, Chlamydia trachomatis, with its host cell. This is ...