Advances in single-cell RNA-sequencing technology have resulted in a wealth of studies aiming to identify transcriptomic cell types in various biological...
Read More »Hipposeq – a comprehensive RNA-seq database of gene expression in hippocampal principal neurons
Clarifying gene expression in narrowly defined neuronal populations can provide insight into cellular identity, computation, and functionality. Here, researchers at the Howard Hughes Medical Institute used next-generation RNA sequencing (RNA-seq) to produce a quantitative, whole genome characterization of gene expression ...
Read More »RNA-Seq Studies Examine Cellular Diversity in the Hippocampus
Researchers at the Howard Hughes Medical Institute’s Janelia Research Campus have uncovered unexpected diversity within a single, canonical cell type of the mammalian brain. Their analysis of cells called CA1 pyramidal neurons shows that for many genes, expression levels vary ...
Read More »Error-correction strategy allows precise measurement of transcriptome in single cells
from Phys.org Howard Hughes Medical Institute (HHMI) scientists have devised a method of visualizing RNA molecules inside cells so that the identity, location, and abundance of more than 1,000 different RNA species can be determined at the same time. The ...
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