Single-cell transcriptomics enables reseachers to explore the hypothalamus one neuron at a time

March 13, 2019 Leave a comment 2,711 Views

A collaborative team from UConn Storrs and The Jackson Laboratory for Genomic Medicine characterized neuron diversity in the lateral hypothalamic area (LHA), a critical coordinator of fundamental...

Trap-Seq – Translating Ribosome Affinity Purification

April 6, 2015 Leave a comment 6,143 Views

Researchers from the University of Michigan isolated mRNA from mouse hypothalamic and brainstem LepRb cells by Translating Ribosome Affinity Purification (TRAP) and analyzed it by RNA-seq (TRAP-seq). Leptin acts via its receptor (LepRb) on multiple subpopulations of LepRb neurons in ...

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Tag Archives: Hypothalamus

Single-cell transcriptomics enables reseachers to explore the hypothalamus one neuron at a time

Trap-Seq – Translating Ribosome Affinity Purification

CircAID-p-seq – a PCR-free library preparation for selective 3′ phospho-RNA sequencing

Nanopore ReCappable Sequencing (NRCeq) – a new technique that can identify capped full-length RNAs

CLEARER – a machine learning approach for predicting essential genes across eukaryotes

scRNA-Seq reveals how genetic ancestry shapes immune response to influenza virus

Single-cell RNA sequencing and bioinformatics as tools to decipher cancer heterogenicity and mechanisms of drug resistance

Microwell-seq – high-throughput screening with single-cell transcriptional profiling

Postdoc position available – computational biology: tumour heterogeneity and resistance mechanisms