Researchers from the Icahn School of Medicine characterize the transcriptional splicing landscape of a prostate cancer cell line treated with a previously identified synergistic drug combination. They use...
Read More »Analysis and Visualization of ChIP-Seq and RNA-Seq Sequence Alignments Using ngs.plot
The continual maturation and increasing applications of next-generation sequencing technology in scientific research have yielded ever-increasing amounts of data that need to be effectively and efficiently analyzed and innovatively mined for new biological insights. Researchers at the Icahn School of ...
Read More »A Combination of ChIP-seq and RNA-seq reveals H3K4me3 landscape in the human brain
Regulators of the histone H3-trimethyl lysine-4 (H3K4me3) mark are significantly associated with the genetic risk architecture of common neurodevelopmental disease, including schizophrenia and autism. Typical H3K4me3 is primarily localized in the form of sharp peaks, extending in neuronal chromatin on ...
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