COVID-19, caused by SARS-CoV-2, has recently affected over 1,200,000 people and killed more than 60,000. The key immune cell subsets change and...
Read More »eq-ImmuCC – cell-ventric view of tissue transcriptome measuring cellular compositions of immune microenvironment from mouse RNA-Seq data
The RNA sequencing approach has been broadly used to provide gene-, pathway-, and network-centric analyses for various cell and tissue samples. However, thus far, rich cellular information carried in tissue samples has not been thoroughly characterized from RNA-Seq data. Therefore, ...
Read More »RNA-Seq reveals widespread intronic polyadenylation diversifies immune cell transcriptomes
Alternative cleavage and polyadenylation (ApA) is known to alter untranslated region (3’UTR) length but can also recognize intronic polyadenylation (IpA) signals to generate transcripts that lose part or all of the coding region. Researchers from Memorial Sloan Kettering Cancer Center ...
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