Single cell sequencing and multiplex single‐molecule RNA FISH analyses on SARS‐CoV‐2 infected human intestinal organoids characterize the tropism of SARS‐CoV‐2 and identify strategies developed by the virus to interfere with the host intrinsic innate...
Read More »RNA-seq reveals why every COVID-19 case is different
As scientists around the world develop life-saving COVID-19 vaccines and therapies, many are still wondering exactly why the disease proves deadly in some people and mild in others. To solve this puzzle, scientists need an in-depth understanding of how the ...
Read More »An NGS assay to quantify biomarkers of the host immune response in FFPE tumor samples
OmniSeq Inc scientists have developed a next-generation sequencing assay to quantify biomarkers of the host immune response in formalin-fixed, paraffin-embedded (FFPE) tumor specimens. This assay aims to provide clinicians with a comprehensive characterization of the immunological tumor microenvironment as a ...
Read More »Using single-cell RNA sequencing to explore immune cell heterogeneity
Advances in single-cell RNA sequencing (scRNA-seq) have allowed for comprehensive analysis of the immune system. Here, researchers from New York University describe the available scRNA-seq technologies together with their corresponding strengths and weaknesses. They discuss in depth how scRNA-seq can be ...
Read More »Researchers combine CRISPR gene editing and single cell genomic profiling
A new combined method may finally give scientists a tool fine enough to probe life’s most nuanced processes What combinations of mutations help cancer cells survive? Which cells in the brain are involved in the onset of Alzheimer’s? How do ...
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