Scientists in Australia have published a multi-omics analysis of immune responses in blood at a transcriptional, cellular, and serological level at 12, 16, and 24 weeks post-infection (wpi) in 69 patients recovering from mild, moderate, severe, or critical COVID-19 in comparison ...
Read More »Immune cell profiling of COVID-19 patients in the recovery stage by single-cell sequencing
COVID-19, caused by SARS-CoV-2, has recently affected over 1,200,000 people and killed more than 60,000. The key immune cell subsets change and...
Read More »Preparation of single cells from tumors for single-cell RNA sequencing
Intratumoral heterogeneity of cancer cells and tumor-infiltrating immune cells is increasingly being viewed as a key factor driving tumor progression and response to therapy. Over the past several years, technological advances have created powerful...
Read More »Deep-learning on scRNA-Seq to deconvolute gene expression data
The development of single cell transcriptome sequencing has allowed researchers the possibility to dig inside the role of the individual cell types in a plethora of disease scenarios. It also expands to the whole transcriptome what before was only possible ...
Read More »Application of single-cell RNA sequencing methodologies in understanding haematopoiesis and immunology
The blood and immune system are characterised by utmost diversity in its cellular components. This heterogeneity can solely be resolved with the application of single-cell technologies that enable precise...
Read More »Revolutionizing immunology with single-cell RNA sequencing
The immune system is composed of a complex hierarchy of cell types that protect the organism against disease and maintain homeostasis. Identifying heterogeneity of immune cells is the...
Read More »Job Posting: Postdoctoral Fellowship Position in Computational Immunology
Yerkes National Primate Research Center, Emory Vaccine Center Emory University, Atlanta, GA, USA Postdoctoral Fellowship Position in Computational Immunology Position Description: A Postdoctoral Fellowship position is available immediately at Emory University and the Yerkes National Primate Research Center in the Division ...
Read More »Using single-cell RNA sequencing to explore immune cell heterogeneity
Advances in single-cell RNA sequencing (scRNA-seq) have allowed for comprehensive analysis of the immune system. Here, researchers from New York University describe the available scRNA-seq technologies together with their corresponding strengths and weaknesses. They discuss in depth how scRNA-seq can be ...
Read More »Post-doc Positions Available – Bioinformatician (High-throughput Genomics/Transcriptomics)
We are looking to recruit an experienced Bioinformatician to join a successful international team studying the mechanisms of gene expression in the immune system. The laboratory consists of five groups studying various aspects of immunology including the impact of ageing ...
Read More »Single-cell technologies to study the immune system
In the first half of Nineteenth century, Schleiden, Schwann, and Virchow developed the cell theory stating that “the cell” is the structural and functional unit of all living things. For the next 170 years scientists have been looking at the ...
Read More »