Allele-specific transcriptional regulation, including of imprinted genes, is essential for normal mammalian development. While the regulatory regions controlling imprinted genes are associated with DNA methylation (DNAme) and specific histone...
Read More »“RNA sequencing alone wouldn’t have convinced me”
Researchers find some neurons in the autistic brain preferentially express the copy of a gene inherited from one parent over the other. Many researchers have assumed that most cells express both copies of a gene equally. Studies in cultured cells ...
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