Writing in Science, Lee et al. report an exciting first step toward combining some of the best aspects of both methods to sequence RNA in single cells in situ. Their approach, called fluorescence in situ RNA sequencing (FISSEQ), effectively treats ...
Read More »A bird’s eye view of cellular RNAs
Fluorescent in situ sequencing from Wyss Institute on Vimeo. In biology, as in real estate, location matters. Working copies of active genes — called messenger RNAs or mRNAs — are positioned strategically throughout living tissues, and their location often helps ...
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