Tag Archives: infection

Detailed knowledge about the dynamics of SARS-CoV-2 infection is important for uncovering the viral and host factors that contribute to COVID-19 pathogenesis. Old-World nonhuman primates recapitulate mild to moderate cases of COVID-19, thereby...

Transcriptomics, i.e., the quantification of cellular RNA transcripts, is a powerful way to gauge the physiological state of either bacterial or eukaryotic cells under a given condition. However, traditional...

Bacteria express many small RNAs for which the regulatory roles in pathogenesis have remained poorly understood due to a paucity of robust phenotypes in standard virulence assays. Here, researchers from the University of Würzburg used a generic ‘dual RNA-seq’ approach ...

Researchers from CSIRO Health and Biosecurity have published findings that start to explain how mosquitoes respond to viral infections. Using an RNA-sequencing approach, they identified a number of genes from multiple cellular pathways that play integral roles in protecting mosquitoes from ...

Researchers at Umeå University recently found that Yersinia pseudotuberculosis can be used as a model of persistent bacterial infections. They performed in vivo RNA-seq of bacteria in small cecal tissue biopsies at early and persistent stages of infection to determine ...

Filoviruses like Ebola “edit” genetic material as they invade their hosts, according to a study published this week in mBio®, the online open-access journal of the American Society for Microbiology. The work, by researchers at the Icahn School of Medicine ...