Most cancer transcriptomes are bloated by widespread intron retention

August 17, 2015 Leave a comment 3,694 Views

by JM Kocarnik at FHCRC Alternative splicing of specific genes can contribute to cancer initiation, progression, and metastasis. With the advent of cancer genome sequencing, it was discovered that many tumor types contain high frequencies of somatic mutations affecting components ...

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Most cancer transcriptomes are bloated by widespread intron retention

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