Tag Archives: King’s College London

Genome-wide association studies have identified hundreds of risk loci for autoimmune disease, yet only a minority (~25%) share genetic effects with changes to gene expression (eQTLs) in immune cells. RNA-Seq based quantification at whole-gene resolution, where abundance is estimated by ...

A postdoctoral position is available in Prof Andrea Streit’s group for 15 months to work on interdisciplinary projects combining developmental biology, epigenetics, transcriptional networks and bioinformatics. The Streit lab studies how multipotent progenitor cells are committed to the ear and ...

Studies attempting to functionally interpret complex-disease susceptibility loci by GWAS and eQTL integration have predominantly employed microarrays to quantify gene-expression. RNA-Seq has the potential to discover a more comprehensive set of eQTLs and illuminate the underlying molecular consequence. Researchers from ...

Unequal growth between genetically identical monozygotic (MZ) twins in the womb may be triggered in the earliest stages of human embryo development, according to a new study led by King’s College London. Around 80% of MZ twins originate from monochorionic/diamniotic ...