Improving RNA-Seq expression estimation by modeling isoform- and exon-specific read sequencing rate

October 19, 2015 Leave a comment 2,954 Views

The high-throughput sequencing technology, RNA-Seq, has been widely used to quantify gene and isoform expression in the study of transcriptome in recent years. Accurate expression measurement from the millions or billions of short generated reads is obstructed by difficulties. One ...

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