Leishmaniasis is among the top ten neglected tropical diseases (NTD), with over 12 million infected people, and 2 million new cases annually...
Read More »Multiplexed Spliced-Leader Sequencing – A high-throughput, selective method for RNA-seq
High throughput sequencing techniques are poorly adapted for in vivo studies of parasites, which require prior in vitro culturing and purification. Trypanosomatids, a group of kinetoplastid protozoans, possess a distinctive feature in their transcriptional mechanism whereby a specific Spliced Leader ...
Read More »SLaP Mapper: a webserver for identifying and quantifying spliced-leader addition and polyadenylation site usage
The Kinetoplastida are a diverse and globally distributed class of free-living and parasitic single-celled eukaryotes that collectively cause a significant burden on human health and welfare. In kinetoplastids individual genes do not have promoters, but rather all genes are arranged ...
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