Mount Sinai researchers have developed a new model that uses DNA and RNA sequencing data from hundreds of patients to identify specific genes and genetic alterations responsible for never-before...
Read More »How RNA sequencing saved a little boy’s life
Lara Stuart and her husband, David Lodge, first noticed the peculiar rash on their son Quincy’s face when he was just shy of 4 months old.Trips to the pediatrician and a dermatologist didn’t offer...
Read More »UCSF researchers recommend that all patients without Ras mutations undergo RNA sequencing to identify any fusions that might be treated with targeted therapies
Identifying Genetic Mutations May Unlock Cure for Challenging Malignancies UCSF Benioff Children’s Hospitals have successfully treated a months-old infant...
Read More »Researchers use AI, RNA-Seq to unlock the secrets of the genome
Every nine minutes, someone in the US dies from blood cancer which accounts for about 10 percent of all cancer deaths. And, every three minutes, one person in the US is diagnosed with a blood cancer — about 170,000 people ...
Read More »Acfs – circRNA identification and quantification from RNA-Seq data
Circular RNAs (circRNAs) are a group of single-stranded RNAs in closed circular form. They are splicing-generated, widely expressed in various tissues and have functional implications in development and diseases. To facilitate genome-wide characterization of circRNAs using RNA-Seq data, researchers from ...
Read More »RNA-Seq unravels molecular changes in acute lymphoblastic leukemia (ALL)
from OncologyNurseAdvisor by Kathy Boltz The molecular characteristics of acute lymphoblastic leukemia (ALL) have been decoded, and these findings were published in Nature Genetics by an international team of European scientists from Berlin, Düsseldorf, Hannover, Heidelberg, Kiel, and Zurich. This ...
Read More »Scientists decipher the molecular basis of an as yet incurable leukemia in children
Detailed molecular analyses allow new insights into the function of tumour cells and new treatments Acute lymphoblastic leukemia (ALL) is the most common type of cancer in children. It can occur in various forms, differing by specific changes in the ...
Read More »RNA-Seq enables discovery of potential biomarker – SSRs (simple sequence repeats)
The recent exponential increase in the number of next generation sequencing studies provides a new source of data for the discovery of functional genomics based markers. RNA-seq and small RNA-seq provide a new source for the discovery of differentially expressed ...
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