Exai Bio, a next-generation liquid biopsy company, today announced it has raised a $67.5 million Series A financing to accelerate development of its non...
Read More »Murrieta Genomics spinout simplSEQ announces data showing value of new DNA and RNA isolation technology across liquid biopsy applications
Cell-free DNA (cfDNA) is becoming an increasingly common input in liquid biopsy-based molecular diagnostics for wide-ranging applications including cancer...
Read More »Phospho-RNAseq – profiling of extracellular mRNAs and lncRNAs
Extracellular RNAs (exRNAs) in biofluids have attracted great interest as potential biomarkers. Although extracellular microRNAs in blood plasma are extensively characterized, extracellular...
Read More »Cell-free DNA and cell-free RNA NGS liquid biopsy technology can guide treatment for most aggressive prostate cancer
Peter Mac scientists have developed a simple blood test that can show which men with the most aggressive type of prostate cancer should respond to conventional therapy, and those who need other options. From as little as 10ml of blood, ...
Read More »Study shows single-cell RNA sequencing can be used on solid tumor liquid biopsy
Small cell lung cancer (SCLC) accounts for 14% of all lung cancers and is often rapidly resistant to chemotherapy, resulting in poor clinical outcomes...
Read More »A new approach to RNA sequencing reveals thousands of previously inaccessible RNA fragments in blood plasma
New method opens unexplored realms for liquid biopsies A new approach to RNA sequencing reveals thousands of previously inaccessible RNA fragments in blood plasma that might serve as disease- and organ-specific biomarkers Advancing technology is allowing scientists increasingly to search ...
Read More »miRandola 2017 – a curated knowledge base of non-invasive biomarkers
miRNAs are small non-coding RNAs (ncRNAs) (21–23 nt long) that regulate gene expression at the post-transcriptional level by binding to messenger RNAs (mRNAs) and inhibiting their translation into proteins or by binding to other ncRNAs. First discovered in 1993 in Caenorhabditis ...
Read More »RNA-Seq of serum microRNA signatures as liquid biopsies
MicroRNAs (miRNAs) released into the peripheral circulation upon cellular injury have shown a promise as a new class of tissue-specific biomarkers. Researchers from Maastricht University were first to demonstrate that next-generation sequencing analysis of serum from human subjects with acetaminophen-induced ...
Read More »RNA is DNA in action
By Wallace Ravven – Losing a breast or a lung to cancer leaves a scar, both physical and emotional. But even a biopsy to determine if a tumor is cancerous, or to track a tumor’s response to drugs, brings short-term ...
Read More »A new method simplifies RNA-Seq analysis and blood biomarker discovery
Scientists at Karolinska Institutet in collaboration with Estonian Competence Centre on Health Technologies have developed a new gene expression analysis method to widen the usage of blood in biomarker discovery and analysis. Their paper is published in the journal Scientific ...
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