Tag Archives: long read

Recent research into structural variants (SVs) has established their importance to medicine and molecular biology, elucidating their role in various diseases, regulation of gene expression, ethnic...

Understanding gene regulation and function requires a genome-wide method capable of capturing both gene expression levels and isoform diversity at the single cell level. Short-read RNAseq, while the current standard for gene expression quantification, is limited in its ability to ...

Short-read sequencing has enabled the de novo assembly of several individual human genomes, but with inherent limitations in characterizing repeat elements. Now, an international team led by researchers at USC have sequenced a Chinese individual HX1 by single-molecule real-time (SMRT) ...

from Genetic Engineering News by Jonas Korlach Long-Read Sequencing Can Offer the Most Comprehensive View Yet of Gene Activity Not too long ago, the life sciences community was still debating whether sequencers would ever overtake microarrays as the preferred means ...