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RNA-Seq brings new molecular insights into diabetes risk

October 3, 2017 Leave a comment 2,322 Views

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Nestlé Institute of Health Sciences (NIHS) researchers have taken another step forward in understanding the variability in glycaemic improvements following weight loss in overweight and obese people, and why the risk of developing diabetes varies from one individual to the ...

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ROS-Induced Hepatotoxicity under Cypermethrin: Involvement of the Crosstalk between Nrf2/Keap1 and NF-κB/iκB-α Pathways Regulated by Proteasome
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Protective effects and molecular mechanisms of <em>Achyranthes bidentata</em> polypeptide k on Schwann cells
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Editorial: Genomic Characterization of Emerging Human Fungal Pathogens
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What is RNA-Seq?

long RNAs are first converted into a library of cDNA fragments through either RNA fragmentation or DNA fragmentation. Sequencing adaptors (blue) are subsequently added to each cDNA fragment and a short sequence is obtained from each cDNA using high-throughput sequencing technology. The resulting sequence reads are aligned with the reference genome or transcriptome, and classified as three types: exonic reads, junction reads and poly(A) end-reads. These three types are used to generate a base-resolution expression profile for each gene. Nat Rev Genet 10(1):57-63 (2009)


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    First use of both bulk and single-cell RNA sequencing of human bladder tumors to study resistance to immunotherapy

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    Post-doc position available – transcriptome bioinformatics and RNA sequencing

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    Introduction to scRNA-Seq Analysis

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