Tag Archives: Massachusetts General Hospital

Researchers have identified a rare cell type in airway tissue, previously uncharacterized in the scientific literature, that appears to play a key role in the biology of cystic fibrosis. Using new technologies that...

A study led by Kevin King, a bioengineer and physician at the University of California San Diego, has found that the immune system plays a surprising role in the aftermath of heart attacks.  The research could lead to new therapeutic ...

Whole-exome sequencing (WES) and whole-genome sequencing (WGS) can only identify rare Mendelian genetic diseases in up to 50% of cases; our ability to interpret the functional and clinical importance of the genetic variants they identify is limited. Here, Cummings et ...

Similarities and differences among astrocytomas and oligodendrogliomas may suggest new treatment approaches Detailed analysis of two brain tumor subtypes has revealed that they may originate from the same type of neural progenitor cells and be distinguished by gene mutation patterns ...

Description: The Shalek Lab (http://shaleklab.com, MIT, Broad Institute, and Ragon Institute) in collaboration with the Walker Lab (http://www.ragoninstitute.org/portfolio-item/walker-lab/, Ragon Institute) has an opening for a highly motivated Research Technician to assist in a global profiling of the immune system in acute ...

Mass. General, Broad Institute team finds strong evidence that cancer stem cells are important drivers of tumors in patients A study analyzing brain tumor genomics on a single-cell level has found evidence that cancer stem cells fuel the growth of ...

Primary Location: MA-Boston-185 Cambridge – MGH Work Locations: 185 Cambridge – MGH 185 Cambridge Street Boston 02144 Job: IT/Health IT/Informatics – Management Organization: Massachusetts General Hospital(MGH) Schedule: Full-time Standard Hours: 40 Shift: Day Job Posted Shift Description: Computational Genomics and ...

Platelet RNA may provide easily accessible ‘liquid biopsy’ for many types of tumor Analysis of tumor RNA carried in platelets – blood components best known for their role in clotting – may prove to be more useful than other “liquid ...

from GenomeWeb by Monica Heger NEW YORK (GenomeWeb) – Researchers from Massachusetts General Hospital have described a method behind two clinical cancer assays — a targeted RNA-seq fusion assay and a hotspot mutation assay — each of which the team ...

from Oncology Nurse Advisor by Kathy Boltz, PhD Analysis of circulating tumor cells (CTCs) in a mouse model of pancreatic cancer identified distinct patterns of gene expression in several groups of CTCs, including significant differences from the primary tumor that ...