Tag Archives: Medical University of Innsbruck

Advances in single-cell technologies have enabled the investigation of T cell phenotypes and repertoires at unprecedented resolution and scale. Bioinformatic methods for the efficient analysis of these large-scale datasets are instrumental for...

Researchers from Medical University of Innsbruck introduce quanTIseq, a method to quantify the fractions of ten immune cell types from bulk RNA-sequencing data. quanTIseq was extensively validated in blood and tumor samples using simulated, flow...

By exerting pro- and anti-tumorigenic actions, tumor-infiltrating immune cells can profoundly influence tumor progression, as well as the success of anti-cancer therapies. Therefore, the quantification of tumor-infiltrating immune cells holds the promise to unveil the multi-faceted role of the immune ...

quanTIseq is the first computational pipeline for the quantification of Tumor-infiltrating Immune cells from raw RNA-seq data and images of haematoxylin and eosin (H&E)-stained tissue...