Tag Archives: microrna

An evaluation of high-throughput isomiR identification tools

MicroRNAs carry out post-transcriptional gene regulation in animals by binding to the 3′ untranslated regions of mRNAs, causing their degradation or translational repression. MicroRNAs influence many biological functions, and dysregulation can therefore disrupt development or even cause death. High-throughput sequencing ...

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New Paper Demonstrates Novel Method for Detecting miRNA to Improve Liver Toxicity Testing

Single molecule microRNA technology proves useful for liver toxicity detection Breakthrough research published in PLOS ONE demonstrates quantitative, PCR-free detection of microRNA https://www.eurekalert.org/pub_releases/2017-07/q-smm062917.php Quanterix Corporation, a company digitizing biomarker analysis with the goal of advancing the science of precision health, ...

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RNA-Seq of serum microRNA signatures as liquid biopsies

MicroRNAs (miRNAs) released into the peripheral circulation upon cellular injury have shown a promise as a new class of tissue-specific biomarkers. Researchers from Maastricht University were first to demonstrate that next-generation sequencing analysis of serum from human subjects with acetaminophen-induced ...

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