Tag Archives: microrna

The majority of lung cancer deaths are caused by metastatic disease. MicroRNAs (miRNAs) are posttranscriptional regulators of gene expression and miRNA dysregulation can contribute to metastatic progression. Here, researchers from Aarhus University used small RNA sequencing to profile the miRNA ...

The genome-wide identification of microRNA transcription start sites (miRNA TSSs) is essential for understanding how miRNAs are regulated in development and disease. In this study, researchers from Vanderbilt University School of Medicine developed mirSTP (mirna transcription Start sites Tracking Program), ...

A team at National Taiwan University, led by Prof Shyh-Jye Lee of the Department of Life Science and director of the Research Center for Developmental Biology and Regenerative Medicine, have demonstrated that microRNAs (miRNAs) regulate the cold response of fish. ...

MicroRNAs (miRNAs) play important roles in human cancers. In previous studies, researchers at the National Yang-Ming University have demonstrated that both 5p-arm and 3p-arm of mature miRNAs could be expressed from the same precursor and we further interrogated the 5p-arm ...

RIVERSIDE, Calif. – The mosquito Aedes aegypti, which can spread dengue fever, chikungunya, Zika fever, and yellow fever virus, requires a blood meal to develop eggs.  One way to control the spread of these diseases is to tamper with the ...

Isoforms of human miRNAs (isomiRs) are constitutively expressed with tissue- and disease-subtype-dependencies. Researchers from Thomas Jefferson University studied 10 271 tumor datasets from The Cancer Genome Atlas (TCGA) to evaluate whether isomiRs can distinguish amongst 32 TCGA cancers. Unlike previous ...

Small non-coding RNAs, in particular microRNAs, are critical for normal physiology and are candidate biomarkers, regulators, and therapeutic targets for a wide variety of diseases. There is an ever-growing interest in the comprehensive and accurate annotation of microRNAs across diverse ...

Recent discovery of thousands of small and large noncoding RNAs, in parallel to technical improvements enabling scientists to study the transcriptome in much higher depth, has resulted in massive data generation. This burst of information prompts the development of easily ...

The interest in investigating the biological roles of small non-coding RNAs (sncRNAs) is increasing, due to the pleiotropic effects of these molecules exert in many biological contexts. While several methods and tools are available to study microRNAs (miRNAs), only few ...

The position is in the Channing Division of Network Medicine at Brigham and Women’s Hospital and Harvard Medical School, Boston, MA. Brigham and Women’s Hospital is consistently ranked one of the top 10 hospitals in the United States, and the ...