MicroRNAs (miRNAs) are small, non-coding RNA molecules that play a key role in gene regulation in both plants and animals. MicroRNA biogenesis involves the enzymatic processing of a primary RNA transcript. The final step is the production of a duplex...
Read More »TCGA2BED – extracting, extending, integrating, and querying The Cancer Genome Atlas
Data extraction and integration methods are becoming essential to effectively access and take advantage of the huge amounts of heterogeneous genomics and clinical data increasingly available. In this work, we focus on The Cancer Genome Atlas, a comprehensive archive of ...
Read More »miRseqViewer – Multi-panel visualization of sequence, structure and expression for analysis of microRNA sequencing data
Deep sequencing of small RNAs has become a routine process in recent years, but no dedicated viewer is as yet available to explore the sequence features simultaneously along with secondary structure and gene expression of microRNA (miRNA). A team led ...
Read More »Sample sequencing of vascular plants demonstrates widespread conservation and divergence of microRNAs
Small RNAs are pivotal regulators of gene expression that guide transcriptional and post-transcriptional silencing mechanisms in eukaryotes, including plants. Here a team led by researchers at the Center for Research and Advanced Studies of the National Polytechnic Institute, Mexico report ...
Read More »HTG launches an automated, sequencing-based miRNA Whole Transcriptome digital gene expression assay for challenging sample types
TUCSON, Ariz. (June 10, 2014) – Today HTG Molecular Diagnostics announced the availability of HTG EdgeSeq miRNA Whole Transcriptome Assay for measuring the expression of 2,275 human microRNAs (miRNAs) described in the miRBase v20 database. The assay measures expression from ...
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