An evaluation of bioinformatics approaches for next-generation sequencing analysis of microRNAs

February 26, 2018 Leave a comment 5,765 Views

MicroRNAs (miRNAs) are key post-transcriptional regulators that affect protein translation by targeting mRNAs. Their role in disease etiology and toxicity are well recognized. Given the rapid advancement of next-generation sequencing techniques, miRNA profiling has been increasingly conducted with RNA-seq, namely ...

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An evaluation of bioinformatics approaches for next-generation sequencing analysis of microRNAs

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