Tag Archives: mirnas

The production of microRNA isoforms in human tissues depends on a person’s gender, population origin, and race as well as on tissue, disease and disease subtype Researchers at Thomas Jefferson University previously reported that miRNA isoforms in healthy individuals change as ...

Chimira is a web-based system for microRNA (miRNA) analysis from small RNA-Seq data. Sequences are automatically cleaned, trimmed, size selected and mapped directly to miRNA hairpin sequences. This generates count-based miRNA expression data for subsequent statistical analysis. Moreover, it is ...

University of Michigan researchers have developed a technique that allows them to efficiently identify snippets of genetic information called microRNAs in blood. The advance could one day lead to a way to scan for multiple types of cancer at once ...

MicroRNAs (miRNAs) are small non-coding RNA molecules that play a key role in gene expression regulation. They have critical functions in various biological processes and their involvement in disease biology is well documented. Several measurement platforms have been developed to ...

Small RNA sequencing and degradome sequencing (also known as parallel analysis of RNA ends) have provided rich information on the microRNA (miRNA) and its cleaved mRNA targets on a genome-wide scale in plants, but no computational tools have been developed ...

Neural tissue differentiated and cultured from derived stem cells is expected to revolutionize the treatment of brain and spinal injuries and diseases. Critical for these cellular therapies is accurate control and monitoring of differentiation but current methods for such cell ...

Recent discoveries show that most types of small non-coding RNAs (sncRNAs) such as miRNAs, snoRNAs and tRNAs get further processed into putatively active smaller RNA species. Their roles, genetic profiles and underlying processing mechanisms are only partially understood. To find ...

Small non-coding RNAs represent RNA species that are not translated to proteins, but which have diverse and broad functional activities in physiological and pathophysiological states. The knowledge of these small RNAs is rapidly expanding in part through the use of ...

It’s come around already. This is your last chance to access the best rate we have available for miRNA World 2014 to ensure you fully harness the clinical applications of miRNA’s. The world leaders of miRNA research are coming together ...

Quantitative real-time PCR (qPCR) has become the “gold standard”for measuring expression levels of individual miRNAs. However, little is known about the validity of reference miRNAs, the improper use of which can result in misleading interpretation of data. Here researchers from ...