INDIANAPOLIS — Opening the door to a better understanding of proteins and our ability to treat and prevent diseases, the National Institutes of Health awarded $1.18 million to faculty at the Indiana University School of Informatics and Computing at IUPUI ...
Read More »Modeling of gene regulatory networks from RNA-Seq data
Systems biology is a research area which aims to understand living systems as a whole, instead of focusing on single biological entities. Gene regulatory network inference is a systems biology approach which predicts interactions between genes with the help of ...
Read More »Modeling Exon-Specific Bias Distribution Improves the Analysis of RNA-Seq Data
RNA-seq technology has become an important tool for quantifying the gene and transcript expression in transcriptome study. The two major difficulties for the gene and transcript expression quantification are the read mapping ambiguity and the overdispersion of the read distribution ...
Read More »Sphinx – modeling transcriptional heterogeneity in single-cell RNA-Seq
The significance of single cell transcription resides not only in the cumulative expression strength of the cell population but also in its heterogeneity. Researchers at the Baylor Institute for Immunology Research propose a new model that improves the detection of ...
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