PCR-based RNA splicing assays are commonly used in diagnostic and research settings to assess the potential effects of variants of uncertain clinical significance in BRCA1 and BRCA2. The Evidence-based...
Read More »NMFP – a non-negative matrix factorization based preselection method to identify mRNA isoforms from RNA-seq data
The advent of next-generation RNA sequencing (RNA-seq) has greatly advanced transcriptomic studies, including system-wide identification and quantification of mRNA isoforms under various biological conditions. A number of computational methods have been developed to systematically identify mRNA isoforms in a high-throughput ...
Read More »Quantitative visualization of alternative exon expression from RNA-Seq data
Analysis of RNA sequencing (RNA-Seq) data revealed that the vast majority of human genes express multiple mRNA isoforms, produced by alternative pre-mRNA splicing and other mechanisms, and that most alternative isoforms vary in expression between human tissues (Pan et al. ...
Read More »PostDoc Position Available – Biostatistician
Postdoctoral Biostatistician (High-throughput Genomics / Transcriptomics) Salary Range – £37491 to £40600 per annum Location – The Babraham Institute, Cambridge, United Kingdom Description – The Babraham Institute is a charity which is world renowned for its research in life sciences to ...
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