Developmental Analysis of Spliceosomal snRNA Isoform Expression with RNA-Seq

November 26, 2014 Leave a comment 4,111 Views

Pre-mRNA splicing is a critical step in eukaryotic gene expression that contributes to proteomic, cellular and developmental complexity. Small nuclear (sn)RNAs are core spliceosomal components, however, the extent to which differential expression of snRNA isoforms regulates splicing is completely unknown. ...

SUPPA – a super-fast pipeline for alternative splicing analysis from RNA-Seq

September 9, 2014 Comments Off on SUPPA – a super-fast pipeline for alternative splicing analysis from RNA-Seq 6,736 Views

High-throughput RNA sequencing allows genome-wide analyses of pre-mRNA splicing across multiple conditions. However, the increasing number of available datasets represents a major challenge in terms of time and storage required for analyses. Now, a team led by researchers at the ...

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Tag Archives: mRNA splicing

Developmental Analysis of Spliceosomal snRNA Isoform Expression with RNA-Seq

SUPPA – a super-fast pipeline for alternative splicing analysis from RNA-Seq

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