Tag Archives: mrna

Power analysis at the isoform level


RNA-Sequencing (RNA-Seq) has become a routine technology for investigating gene expression differences in comparative transcriptomic studies. Differential expression (DE) analysis of the isoforms of genes is just emerging now that expression (read counts) can be estimated with higher accuracy at ...

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Researchers use parallel analysis of mRNA structure (PARS), ribosome profiling and RNA sequencing (RNA-seq) to reveal that bacterial mRNA structure functions beyond information transfer

Messenger RNA acts as an informational molecule between DNA and translating ribosomes. Emerging evidence places mRNA in central cellular processes beyond its major function as informational entity. Although individual examples show that specific structural features of mRNA regulate translation and ...

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