Widespread skewed expression of mRNA components correlate with fine tuning of protein production Rockefeller University – Science News – Long cast as a simple link between DNA and protein, messenger RNA has never offered much intrigue. But new research at ...
Read More »miRge – A Multiplexed Method of Processing Small RNA-Seq Data to Determine MicroRNA Entropy
Small RNA RNA-seq for microRNAs (miRNAs) is a rapidly developing field where opportunities still exist to create better bioinformatics tools to process these large datasets and generate new, useful analyses. Researchers at Johns Hopkins University School of Medicine have built ...
Read More »Researchers use parallel analysis of mRNA structure (PARS), ribosome profiling and RNA sequencing (RNA-seq) to reveal that bacterial mRNA structure functions beyond information transfer
Messenger RNA acts as an informational molecule between DNA and translating ribosomes. Emerging evidence places mRNA in central cellular processes beyond its major function as informational entity. Although individual examples show that specific structural features of mRNA regulate translation and ...
Read More »Techniques for positional information integration on the transcriptome
The recent explosion of high-throughput sequencing methods applied to RNA molecules is allowing us to go beyond the description of sequence variants and their relative abundances, as measured by RNA-seq. We can now probe for RNA engagement in polysomes, for ...
Read More »The 2nd International mRNA Health Conference
The time is right to give therapeutic mRNA a special forum. mRNA – the molecule whose medical use seemed almost out of reach until a few years ago – is now in substantial progress to become a new class of ...
Read More »Depletion of Ribosomal RNA for Mosquito Gut Metagenomic RNA-seq
A ribosomal RNA (rRNA) depletion protocol was developed to enrich messenger RNA (mRNA) for RNA-seq of the mosquito gut metatranscriptome. Sample specific rRNA probes, which were used to remove rRNA via subtraction, were created from the mosquito and its gut ...
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