High-resolution genomic analysis of human mitochondrial RNA sequence variation

May 1, 2014 Leave a comment 5,896 Views

Mutations in the mitochondrial genome are associated with multiple diseases and biological processes; however, little is known about the extent of sequence variation in the mitochondrial transcriptome. By ultra-deeply sequencing mitochondrial RNA (>6000×) from the whole blood of ~1000 individuals ...

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High-resolution genomic analysis of human mitochondrial RNA sequence variation

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